Publications & Preprints

McBride, M.J., Hunter, C.J., Zhang, Z., TeSlaa, T., Xu, X., Ducker, G.S., and Rabinowitz, J.D. Glycine homeostasis requires reverse SHMT flux. Cell Metabolism, 2024 Jan 2. [link]

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Lu, W., Park, N.R., TeSlaa, T., Jankowski, C.S.R., Samarah, L., McReynolds, M., Xing, X., Schembri, J., Woolf, M.T., Rabinowitz, J.D., and Davidson, S.M. Acidic Methanol Treatment Facilitates Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging of Energy Metabolism. Analytical Chemistry, 2023 Sept 27. [link]

 

TeSlaa, T., Ralser, M., Fan, J., and Rabinowitz, J.D. The pentose phosphate pathway in heath and disease. Nature Metabolism, 2023 [link]

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Zhang, Z., TeSlaa, T., Rabinowitz, J.D. Reply to: revisiting the role of serine metabolism in hepatic lipogenesis. Nature Metabolism, 2023 [link​]

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Bartman, C.R., Weilandt, D.R., Shen, Y., Lee, W.D., Han, Y., TeSlaa, T., Jankowski C.S.R., Samarah, L., Park, N.R., da Silva-Diz, V., Aleksandrova, M., Gultekin, Y., Marishta, A., Wang, L., Yang, L., Roichman, A., Bhatt, V., Lan, T., Hu, Z., Xi, X., Lu, W., Davidson, S., Wühr, M., Vander Heiden, M.G., Herranz, D., Guo, J.Y., Kang, Y., Rabinowitz, J.D. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature, 2023 Feb 1. [link]

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Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T.G., Downes, M., Evans, R., Von Hoff, D., Guo, J.Y., & Rabinowitz, J. D. (2022). Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med, 3(2), 119-136. [link]

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Wang, L., Xing, X., Zeng, X., Jackson, S. R., TeSlaa, T., Al-Dalahmah, O., Samarah, L.Z., Goodwin, K., Yang, L., McReynolds, M.R., Li, X., Wolff, J.J., Rabinowitz, J.D., & Davidson, S. M. (2022). Spatially resolved isotope tracing reveals tissue metabolic activity. Nature methods, 19(2), 223-230. [link][PDF]

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Zhang, Z.*, TeSlaa, T.*, Xu, X., Zeng, X., Yang, L., Xing, G., Tesz, G.J., Clasquin, M.F., & Rabinowitz, J. D. (2021). Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nature metabolism, 3(12), 1608-1620. [link][PDF]

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Bartman, C. R., TeSlaa, T., & Rabinowitz, J. D. (2021). Quantitative flux analysis in mammals. Nature Metabolism, 3(7), 896-908. [link][PDF]

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TeSlaa, T., Bartman, C. R., Jankowski, C. S., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., & Rabinowitz, J. D. (2021). The source of glycolytic intermediates in mammalian tissues. Cell metabolism, 33(2), 367-378. [link][PDF]

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Quinn III, W. J.*, Jiao, J.*, TeSlaa, T.*, Stadanlick, J., Wang, Z., Wang, L., Akimova, T., Angelin, A., Schafer, P.M., Cully, M.D., Perry, C., Kopinski, P.K., Guo, L., Blair, I.A., Ghanem, L.R., Leibowitz, M.S., Hancock, W.W., Moon, E.K., Levine, M.H., Eruslanov, E.B., Wallace, D.C., Baur, J.A., & Beier, U. H. (2020). Lactate limits T cell proliferation via the NAD (H) redox state. Cell reports, 33(11), 108500. [link][PDF]

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Hui, S., Cowan, A. J., Zeng, X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., & Rabinowitz, J. D. (2020). Quantitative fluxomics of circulating metabolites. Cell metabolism, 32(4), 676-688. [link][PDF]

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Ghergurovich, J. M., García-Cañaveras, J. C., Wang, J., Schmidt, E., Zhang, Z., TeSlaa, T., Patel, H., Chen, L., Britt, E.C., Piqueras-Nebot, M., Gomez-Cabrera, M.C., Lahoz, A., Fan, J., Beier, U.H., Kim, H., & Rabinowitz, J. D. (2020). A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nature chemical biology, 16(7), 731-739. [link][PDF]

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Stine, R. R., Sakers, A. P., TeSlaa, T., Kissig, M., Stine, Z. E., Kwon, C. W., Cheng, L., Lim, H.-W., Kaestner, K.H., Rabinowitz, J.D., & Seale, P. (2019). PRDM16 maintains homeostasis of the intestinal epithelium by controlling region-specific metabolism. Cell Stem Cell, 25(6), 830-845. [link][PDF]

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Shimada, E., Ahsan, F. M., Nili, M., Huang, D., Atamdede, S., TeSlaa, T., Case, D., Yu, X., Gregory, B.D., Perrin, B.J., Koehler, C.M., & Teitell, M. A. (2018). PNPase knockout results in mtDNA loss and an altered metabolic gene expression program. PloS one, 13(7), e0200925. [link][PDF]

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TeSlaa, T., Chaikovsky, A. C., Lipchina, I., Escobar, S. L., Hochedlinger, K., Huang, J., Graeber, T.G., Braas, D., & Teitell, M. A. (2016). α-Ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells. Cell metabolism, 24(3), 485-493. [link][PDF]

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Wu, T. H., Sagullo, E., Case, D., Zheng, X., Li, Y., Hong, J. S., TeSlaa, T., Patananan, A.N., McCaffery, J.M., Niazi, K., Braas, D., Koehler, C.M., Graeber, T.G., Chiou, P.-Y., & Teitell, M. A. (2016). Mitochondrial transfer by photothermal nanoblade restores metabolite profile in mammalian cells. Cell metabolism, 23(5), 921-929. [link][PDF]

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Setoguchi, K., TeSlaa, T., Koehler, C. M., & Teitell, M. A. (2016). P53 regulates rapid apoptosis in human pluripotent stem cells. Journal of molecular biology, 428(7), 1465-1475. [link][PDF]

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TeSlaa, T., Setoguchi, K., & Teitell, M. A. (2016, April). Mitochondria in human pluripotent stem cell apoptosis. Seminars in cell & developmental biology (Vol. 52, pp. 76-83). [link][PDF]

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Teslaa, T., & Teitell, M. A. (2015). Pluripotent stem cell energy metabolism: an update. The EMBO journal, 34(2), 138-153. [link][PDF]

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Pate, K. T., Stringari, C., Sprowl‐Tanio, S., Wang, K., TeSlaa, T., Hoverter, N. P., McQuade, M.M., Garner, C., Digman, M.A., Teitell, M.A., Edwards, R.A., Gratton, E., & Waterman, M. L. (2014). Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. The EMBO journal, 33(13), 1454-1473. [link][PDF]

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TeSlaa, T., & Teitell, M. A. (2014). Techniques to monitor glycolysis. Methods in enzymology, 542, 91-114. [link][PDF]

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Xu, J., Teslaa, T., Wu, T. H., Chiou, P. Y., Teitell, M. A., & Weiss, S. (2012). Nanoblade delivery and incorporation of quantum dot conjugates into tubulin networks in live cells. Nano letters, 12(11), 5669-5672. [link][PDF]

 

Wu, T. H., Chen, Y., Park, S. Y., Hong, J., TeSlaa, T., Zhong, J. F., Di Carlo, D.D., Teitell, M.A., & Chiou, P. Y. (2012). Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter. Lab on a Chip, 12(7), 1378-1383. [link][PDF]

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French, C. T., Toesca, I. J., Wu, T. H., TeSlaa, T., Beaty, S. M., Wong, W., Liu, M., Schröder, I., Chiou, P.Y., Teitell, M.A., & Miller, J. F. (2011). Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade. Proceedings of the National Academy of Sciences, 108(29), 12095-12100. [link][PDF]

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Wu, T. H., TeSlaa, T., Kalim, S., French, C. T., Moghadam, S., Wall, R., Miller, J.F., Witte, O.N., Teitell, M.A., & Chiou, P. Y. (2011). Photothermal nanoblade for large cargo delivery into mammalian cells. Analytical chemistry, 83(4), 1321-1327. [link][PDF]

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Wu, T. H., Teslaa, T., Teitell, M. A., & Chiou, P. Y. (2010). Photothermal nanoblade for patterned cell membrane cutting. Optics express, 18(22), 23153-23160. [link][PDF]

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*equal contribution